
Santa Cruz de la Sierra Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
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Top Santa Cruz de la Sierra Vacation Deals
Price found within the past 48 hours. Click for updated prices.



Hyatt Regency Madrid Residences
Salamanca
CA $2,838
per person
Oct 13 - Oct 19
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Madrid (MAD)
9.4/10 Exceptional! (128 reviews)
The rooms are beautiful. However, the check in process didn’t give “vacation vibes”. You’re definitely checking into an apartment so no special experience upon check in, but the property itself is lovely & most places I wanted to go were 15 mins or less on an uber ride away.
Reviewed on Aug 18, 2026

Hotel Regina
Madrid Centro
CA $1,673
per person
Nov 15 - Nov 21
found 24 hours ago
Roundtrip flight included
Montreal (YMQ) to Madrid (MAD)
9.8/10 Exceptional! (2,359 reviews)
Great location near all tourist attractions and metro. Breakfast was excellent. Room was very clean with comfortable beds.
Reviewed on Aug 28, 2026
Ready to book your vacation to Santa Cruz de la Sierra?
Santa Cruz de la Sierra Hotel Deals

Rural house (full rental) El Olivar del Marqués for 26 people
Santa Cruz de la Sierra Cáceres

Parador de Trujillo
Santa Beatriz de Silva 1 Trujillo Caceres
Fully refundableReserve now, pay when you stay
CA $117
CA $128 total
Aug 31 - Sep 1
includes taxes & fees
9.2/10 Wonderful! (243 reviews)
"Car parking, first you need to park in the road, then check in & then move your car to the car park after reception opens the gate which is not too quickly !! We checked in but were not given the wi-fi password and there is no information in the room so we had to return to reception. Breakfast - ..."
Reviewed on Aug 18, 2026

Hotel Izan Trujillo
Plaza del Campillo, 1 Trujillo Caceres
Fully refundableReserve now, pay when you stay
CA $102
CA $113 total
Aug 30 - Aug 31
includes taxes & fees
8.6/10 Excellent! (216 reviews)
"Nice hotel with a secure room for cycles for those on tour like me. Nice rooms and good facilities. Restaurant is good but also great places to eat on the Plaza."
Reviewed on Aug 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Cruz de la Sierra vacation package cost?
You can grab a vacation package to this top destination from CA $1,516 on Expedia. However, how much your vacation to Santa Cruz de la Sierra costs will depend on your hotel choice, length of stay and season.
What are the cheapest months to go to Santa Cruz de la Sierra?
Plan your getaway for the low or shoulder season and you're likely to find cheap Santa Cruz de la Sierra vacation packages. Remember that public holidays and local events and festivals can have an impact on prices, so do a little research before booking.
How many days is enough for Santa Cruz de la Sierra?
Usually, a handful of days is enough to tick off the major attractions during your Santa Cruz de la Sierra vacation. However, if you want to have time to unwind or go on day trips, think about extending your itinerary.
How to find the best Santa Cruz de la Sierra package deals?
Use Expedia's handy filters to help you find some unbeatable Santa Cruz de la Sierra package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or look for Santa Cruz de la Sierra package deals in the low season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Santa Cruz de la Sierra vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll typically score a better deal than booking each component individually. And you'll still have the freedom to create a tailored Santa Cruz de la Sierra vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Santa Cruz de la Sierra?
If you're planning a spontaneous Santa Cruz de la Sierra adventure, browse our last-minute deals that can be booked up to one week before you take off. Don't want to leave things to the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa Cruz de la Sierra?
- Choose when to travel: Check your diary and get packing. Your favourite time of year and the activities on offer will also help you decide when to vacation in Santa Cruz de la Sierra.
- Set a budget: Factor in expenses such as transportation, flights and meals when calculating how much to put aside for your trip to Santa Cruz de la Sierra. Then, choose a property that fits your budget, whether that's an economical option or a lavish retreat.
- Determine how many days away: Start by compiling a list of the attractions and activities you'd like to experience in Santa Cruz de la Sierra. Then, estimate how long you'll need for each, along with any travel time.
- Combine your flights and hotel: Awesome destination, check. Length of stay, check. Now all that's left is to find a Santa Cruz de la Sierra vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.








